Cargando…

Anti-Cancer and Ototoxicity Characteristics of the Curcuminoids, CLEFMA and EF24, in Combination with Cisplatin

In this study, we investigated whether the curcuminoids, CLEFMA and EF24, improved cisplatin efficacy and reduced cisplatin ototoxicity. We used the lung cancer cell line, A549, to determine the effects of the curcuminoids and cisplatin on cell viability and several apoptotic signaling mechanisms. C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monroe, Jerry D., Hodzic, Denis, Millay, Matthew H., Patty, Blaine G., Smith, Michael E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864451/ https://www.ncbi.nlm.nih.gov/pubmed/31671767 http://dx.doi.org/10.3390/molecules24213889

Ejemplares similares

Ubiquitin Receptor RPN13 Mediates the Inhibitory Interaction of Diphenyldihaloketones CLEFMA and EF24 With the 26S Proteasome
por: Rao, Geeta, et al.
Publicado: (2018)

Anti-cancer characteristics and ototoxicity of platinum(II) amine complexes with only one leaving ligand
por: Monroe, Jerry D., et al.
Publicado: (2018)

Cisplatin ototoxicity histopathology
por: Hodge, Sarah E., et al.
Publicado: (2021)

Molecular Characteristics of Cisplatin-Induced Ototoxicity and Therapeutic Interventions
por: Tan, Winston J. T., et al.
Publicado: (2023)

The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin
por: Toplu, Yuksel, et al.
Publicado: (2016)

Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection
por: Sheth, Sandeep, et al.
Publicado: (2017)

The Effects of Riluzole on Cisplatin-induced Ototoxicity
por: Üstün Bezgin, Selin, et al.
Publicado: (2019)

Mechanisms of Aminoglycoside- and Cisplatin-Induced Ototoxicity
por: Steyger, Peter S.
Publicado: (2021)

Ototoxicity from Combined Cisplatin and Radiation Treatment: An In Vitro Study
por: Low, Wong-Kein, et al.
Publicado: (2010)

Calpain mediated cisplatin-induced ototoxicity in mice
por: Chang, Liang, et al.
Publicado: (2013)

Otoprotective Effects of Zingerone on Cisplatin-Induced Ototoxicity
por: Lee, Chang Ho, et al.
Publicado: (2020)

Current Strategies to Combat Cisplatin-Induced Ototoxicity
por: Yu, Dehong, et al.
Publicado: (2020)

Mitophagy Impairment Aggravates Cisplatin-Induced Ototoxicity
por: Cho, Sung Il, et al.
Publicado: (2021)

Oxidative Stress and Inflammation Caused by Cisplatin Ototoxicity
por: Ramkumar, Vickram, et al.
Publicado: (2021)

The role of apoptosis in cisplatin-induced ototoxicity in rats
por: De Freitas, Marcos Rabelo, et al.
Publicado: (2015)

The effectiveness of eugenol against cisplatin-induced ototoxicity()
por: Sakat, Muhammed Sedat, et al.
Publicado: (2018)

Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers
por: Generotti, Charles, et al.
Publicado: (2022)

Protective Effect of Minocycline Against Cisplatin-induced Ototoxicity
por: Lee, Chi-Kyou, et al.
Publicado: (2011)

Dexmedetomidine Preconditioning Attenuates Cisplatin-Induced Ototoxicity in Zebrafish
por: Min, Too Jae, et al.
Publicado: (2014)

Protective Effect of Tempol against Cisplatin-Induced Ototoxicity
por: Youn, Cha Kyung, et al.
Publicado: (2016)

Cisplatin-Associated Ototoxicity: A Review for the Health Professional
por: Paken, Jessica, et al.
Publicado: (2016)

The genetic vulnerability to cisplatin ototoxicity: a systematic review
por: Tserga, Evangelia, et al.
Publicado: (2019)

Cisplatin-Induced Ototoxicity: Effects, Mechanisms and Protection Strategies
por: Callejo, Angela, et al.
Publicado: (2015)

Supporting Cells and Their Potential Roles in Cisplatin-Induced Ototoxicity
por: Waissbluth, Sofia, et al.
Publicado: (2022)

The effect of genistein on cisplatin induced ototoxicity and oxidative stress
por: Tan, Mehmet, et al.
Publicado: (2021)

The use of Maytenus ilicifolia to prevent cisplatin-induced ototoxicity
por: Kasse, Cristiane Akemi, et al.
Publicado: (2015)

Curcumin Prevents Ototoxicity Induced by Cisplatin as Evaluated with OAE
por: Arwanda, Muhammad Dana, et al.
Publicado: (2023)

The Curcuminoid EF24 in Combination with TRAIL Reduces Human Renal Cancer Cell Migration by Decreasing MMP-2/MMP-9 Activity through a Reduction in H(2)O(2)
por: Ibáñez Gaspar, Verónica, et al.
Publicado: (2023)

The Role of Thiamine Pyrophosphate in Prevention of Cisplatin Ototoxicity in an Animal Model
por: Kuduban, Ozan, et al.
Publicado: (2013)

Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?
por: Cobanoglu, H. Bengu, et al.
Publicado: (2019)

GSTA4 mediates reduction of cisplatin ototoxicity in female mice
por: Park, Hyo-Jin, et al.
Publicado: (2019)

Insight into the current practice of ototoxicity monitoring during cisplatin therapy
por: Santucci, N. M., et al.
Publicado: (2021)

Protective effect of berberine chloride against cisplatin-induced ototoxicity
por: Kim, Jong-Heun, et al.
Publicado: (2021)

Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity
por: Al Aameri, Raheem F. H., et al.
Publicado: (2023)

Establishment of an optimized guinea pig model of cisplatin-induced ototoxicity
por: Ahmadi, Navid, et al.
Publicado: (2023)

CLEFMA Induces the Apoptosis of Oral Squamous Carcinoma Cells through the Regulation of the P38/HO-1 Signalling Pathway
por: Chen, Pei-Ni, et al.
Publicado: (2022)

Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo
por: Nan, Benyu, et al.
Publicado: (2022)

Synthesis of Thiophene and NO-Curcuminoids for Antiinflammatory and Anti-Cancer Activities
por: Ahmed, Mahera M., et al.
Publicado: (2013)

Analysis of risk factors for cisplatin-induced ototoxicity in patients with testicular cancer.
por: Bokemeyer, C., et al.
Publicado: (1998)

Cisplatin and Oxaliplatin Toxicity: Importance of Cochlear Kinetics as a Determinant for Ototoxicity
por: Hellberg, Victoria, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_0p0mgcr90acu20v1s1nc1qedno