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Novel C7-Substituted Coumarins as Selective Monoamine Oxidase Inhibitors: Discovery, Synthesis and Theoretical Simulation

There is a continued need to develop new selective human monoamine oxidase (hMAO) inhibitors that could be beneficial for the treatment of neurological diseases. However, hMAOs are closely related with high sequence identity and structural similarity, which hinders the development of selective MAO i...

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Detalles Bibliográficos
Autores principales: Wang, Dong, Hong, Ren-Yuan, Guo, Mengyao, Liu, Yi, Chen, Nianhang, Li, Xun, Kong, De-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864482/
https://www.ncbi.nlm.nih.gov/pubmed/31694262
http://dx.doi.org/10.3390/molecules24214003