Cargando…

Comparison between transgenic and AAV-PHP.eB-mediated expression of GCaMP6s using in vivo wide-field functional imaging of brain activity

We employ transcranial wide-field single-photon imaging to compare genetically encoded calcium sensors under transgenic or viral vector expression strategies. Awake, head-fixed animals and brief visual flash stimuli are used to assess function. The use of awake transcranial imaging may reduce confou...

Descripción completa

Detalles Bibliográficos
Autores principales: Michelson, Nicholas J., Vanni, Matthieu P., Murphy, Timothy H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864505/
https://www.ncbi.nlm.nih.gov/pubmed/31763351
http://dx.doi.org/10.1117/1.NPh.6.2.025014