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Heat Shock Protein Inspired Nanochaperones Restore Amyloid‐β Homeostasis for Preventative Therapy of Alzheimer's Disease

Amyloid beta (Aβ) aggregation is generally believed as the crucial and primary cause of Alzheimer's disease (AD). However, current Aβ‐targeted therapeutic strategies show limited disease‐modifying efficacy due to the irreversible damages in the late stage of AD, thus the treatment should be giv...

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Detalles Bibliográficos
Autores principales: Yang, Huiru, Li, Xinyu, Zhu, Lin, Wu, Xiaohui, Zhang, Shaozhi, Huang, Fan, Feng, Xizeng, Shi, Linqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864524/
https://www.ncbi.nlm.nih.gov/pubmed/31763156
http://dx.doi.org/10.1002/advs.201901844