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Intracellular Environment Improvement of Mycobacterium neoaurum for Enhancing Androst-1,4-Diene-3,17-Dione Production by Manipulating NADH and Reactive Oxygen Species Levels

As one of the most significant steroid hormone precursors, androst-1,4-diene-3,17-dione (ADD) could be used to synthesize many valuable hormone drugs. The microbial transformation of sterols to ADD has received extensive attention in recent years. In a previous study, Mycobacterium neoaurum JC-12 wa...

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Detalles Bibliográficos
Autores principales: Shao, Minglong, Zhao, Youxi, Liu, Yu, Yang, Taowei, Xu, Meijuan, Zhang, Xian, Rao, Zhiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864555/
https://www.ncbi.nlm.nih.gov/pubmed/31731395
http://dx.doi.org/10.3390/molecules24213841