Cargando…

Intracellular Environment Improvement of Mycobacterium neoaurum for Enhancing Androst-1,4-Diene-3,17-Dione Production by Manipulating NADH and Reactive Oxygen Species Levels

As one of the most significant steroid hormone precursors, androst-1,4-diene-3,17-dione (ADD) could be used to synthesize many valuable hormone drugs. The microbial transformation of sterols to ADD has received extensive attention in recent years. In a previous study, Mycobacterium neoaurum JC-12 wa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shao, Minglong, Zhao, Youxi, Liu, Yu, Yang, Taowei, Xu, Meijuan, Zhang, Xian, Rao, Zhiming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864555/ https://www.ncbi.nlm.nih.gov/pubmed/31731395 http://dx.doi.org/10.3390/molecules24213841

Ejemplares similares

Enhanced Production of Androst-1,4-Diene-3,17-Dione by Mycobacterium neoaurum JC-12 Using Three-Stage Fermentation Strategy
por: Shao, Minglong, et al.
Publicado: (2015)

A Novel 3-Phytosterone-9α-Hydroxylase Oxygenation Component and Its Application in Bioconversion of 4-Androstene-3,17-Dione to 9α-Hydroxy-4-Androstene-3,17-Dione Coupling with A NADH Regeneration Formate Dehydrogenase
por: Zhang, Xian, et al.
Publicado: (2019)

Efficient 9α-hydroxy-4-androstene-3,17-dione production by engineered Bacillus subtilis co-expressing Mycobacterium neoaurum 3-ketosteroid 9α-hydroxylase and B. subtilis glucose 1-dehydrogenase with NADH regeneration
por: Zhang, Xian, et al.
Publicado: (2016)

11α,15α-Dihydroxyandrost-4-ene-3,17-dione
por: Shen, Yan-Bing, et al.
Publicado: (2011)

Heterologous expression and characterization of a 3-ketosteroid-∆(1)-dehydrogenase from Gordonia neofelifaecis and its utilization in the bioconversion of androst-4,9(11)-dien-3,17-dione
por: Wang, Weiyi, et al.
Publicado: (2017)

Fungal transformation of androsta-1,4-diene-3,17-dione by Aspergillus brasiliensis
por: Hosseinabadi, Tahereh, et al.
Publicado: (2014)

Complete Genome Sequence of Mycobacterium sp. Strain VKM Ac-1817D, Capable of Producing 9α-Hydroxy-androst-4-ene-3,17-dione from Phytosterol
por: Shtratnikova, Victoriya Y., et al.
Publicado: (2015)

One-pot biosynthesis of 7β-hydroxyandrost-4-ene-3,17-dione from phytosterols by cofactor regeneration system in engineered mycolicibacterium neoaurum
por: Zhao, Yun-Qiu, et al.
Publicado: (2022)

Driving the conversion of phytosterol to 9α-hydroxy-4-androstene-3,17-dione in Mycolicibacterium neoaurum by engineering the supply and regeneration of flavin adenine dinucleotide
por: Song, Lu, et al.
Publicado: (2023)

Mycobacterium neoaurum Contamination
por: Han, Xiang Y.
Publicado: (2005)

Exochelin Production in Mycobacterium neoaurum
por: Chan, Kok-Gan
Publicado: (2009)

11β,17aα-Dihydroxy-17aβ-methyl-d-homoandrosta-1,4-diene-3,17-dione monohydrate
por: Qiu, Ya, et al.
Publicado: (2009)

Metabolic engineering of Bacillus subtilis for redistributing the carbon flux to 2,3-butanediol by manipulating NADH levels
por: Yang, Taowei, et al.
Publicado: (2015)

Redetermination of 5α-androstane-3,17-dione
por: Jasinski, Jerry P., et al.
Publicado: (2010)

Bacteremia with an Unusual Pathogen: Mycobacterium neoaurum
por: Awadh, Hesham, et al.
Publicado: (2016)

6-Methylideneandrost-4-ene-3,17-dione
por: Andrade, L. C. R., et al.
Publicado: (2012)

Infección de marcapasos por Mycobacterium neoaurum
por: Bastón-Paz, Natalia, et al.
Publicado: (2018)

Insight into the biology of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members
por: Behra, Phani Rama Krishna, et al.
Publicado: (2019)

Rapidly Progressive Dementia Due to Mycobacterium neoaurum Meningoencephalitis
por: Heckman, George A., et al.
Publicado: (2004)

A case report of cutaneous infection with Mycobacterium neoaurum
por: Mohebbipour‐Loren, Alireza, et al.
Publicado: (2023)

Draft Genome Sequence of Mycobacterium neoaurum Strain DSM 44074(T)
por: Phelippeau, Michael, et al.
Publicado: (2014)

Pulmonary Infection Caused by Mycobacterium neoaurum: The First Case in Korea
por: Kim, Chang-Ki, et al.
Publicado: (2014)

N20D/N116E Combined Mutant Downward Shifted the pH Optimum of Bacillus subtilis NADH Oxidase
por: Yang, Taowei, et al.
Publicado: (2023)

Engineered disulfide bonds improve thermostability and activity of L‐isoleucine hydroxylase for efficient 4‐HIL production in Bacillus subtilis 168
por: Qiao, Zhina, et al.
Publicado: (2019)

5α-Androst-3-en-17β-yl acetate
por: Andrade, L. C. R., et al.
Publicado: (2009)

Synthetic engineering of Corynebacterium crenatum to selectively produce acetoin or 2,3-butanediol by one step bioconversion method
por: Zhang, Xian, et al.
Publicado: (2019)

21-Hydroxypregna-1,4-diene-3,20-dione
por: Yousuf, S., et al.
Publicado: (2011)

Mycobacterium neoaurum line-related bacteremia with pulmonary involvement: Case report and review of literature
por: Walayat, Saqib, et al.
Publicado: (2018)

Mycobacterium neoaurum causing prosthetic valve endocarditis: a case report and review of the literature
por: Kumar, Anupam, et al.
Publicado: (2013)

Comparative genomics of Mycobacterium mucogenicum and Mycobacterium neoaurum clade members emphasizing tRNA and non-coding RNA
por: Behra, Phani Rama Krishna, et al.
Publicado: (2019)

8,14-Secogammacera-7,14(27)-diene-3,21-dione–8,14-secogammacera-7,14-diene-3,21-dione (1.5/0.5) from the bark of Lansium domesticum Corr.
por: Tjokronegero, Roekmi-ati, et al.
Publicado: (2009)

Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum Strain VKM Ac-1815D
por: Shtratnikova, Victoriya Y., et al.
Publicado: (2014)

Comment on “Mycobacterium neoaurum line-related bacteremia with pulmonary involvement: Case report and review of literature’’
por: Keikha, Masoud
Publicado: (2018)

Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation
por: Xu, Yuanyuan, et al.
Publicado: (2023)

Healthcare-Associated Infections Caused by Mycolicibacterium neoaurum
por: Shapiro, Kate, et al.
Publicado: (2023)

Improving the production of 9α-hydroxy-4-androstene-3,17-dione from phytosterols by 3-ketosteroid-Δ(1)-dehydrogenase deletions and multiple genetic modifications in Mycobacterium fortuitum
por: Liu, Xiangcen, et al.
Publicado: (2023)

Enhancing the bioconversion of phytosterols to steroidal intermediates by the deficiency of kasB in the cell wall synthesis of Mycobacterium neoaurum
por: Xiong, Liang-Bin, et al.
Publicado: (2020)

Case report: Mycobacterium neoaurum infection during ICI therapy in a hepatocellular carcinoma patient with psoriasis
por: Pang, Ling, et al.
Publicado: (2022)

Deletion of the gene encoding the reductase component of 3-ketosteroid 9α-hydroxylase in Rhodococcus equi USA-18 disrupts sterol catabolism, leading to the accumulation of 3-oxo-23,24-bisnorchola-1,4-dien-22-oic acid and 1,4-androstadiene-3,17-dione
por: Yeh, Chin-Hsing, et al.
Publicado: (2014)

Enhanced 2,3-butanediol production from biodiesel-derived glycerol by engineering of cofactor regeneration and manipulating carbon flux in Bacillus amyloliquefaciens
por: Yang, Taowei, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_l0j5868d9c2b9on4pbr251q64m