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Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex

A subset of Rab GTPases have been implicated in cilium formation in cultured mammalian cells [1, 2, 3, 4, 5, 6]. Rab11 and Rab8, together with their GDP-GTP exchange factors (GEFs), TRAPP-II and Rabin8, promote recruitment of the ciliary vesicle to the mother centriole and its subsequent maturation,...

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Detalles Bibliográficos
Autores principales: Gerondopoulos, Andreas, Strutt, Helen, Stevenson, Nicola L., Sobajima, Tomoaki, Levine, Tim P., Stephens, David J., Strutt, David, Barr, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864590/
https://www.ncbi.nlm.nih.gov/pubmed/31564489
http://dx.doi.org/10.1016/j.cub.2019.07.090