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Early Celastrol Administration Prevents Ketamine-Induced Psychotic-Like Behavioral Dysfunctions, Oxidative Stress and IL-10 Reduction in The Cerebellum of Adult Mice

Administration of subanesthetic doses of ketamine during brain maturation represents a tool to mimic an early insult to the central nervous system (CNS). The cerebellum is a key player in psychosis pathogenesis, to which oxidative stress also contributes. Here, we investigated the impact of early ce...

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Detalles Bibliográficos
Autores principales: Schiavone, Stefania, Tucci, Paolo, Trabace, Luigia, Morgese, Maria Grazia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864687/
https://www.ncbi.nlm.nih.gov/pubmed/31694174
http://dx.doi.org/10.3390/molecules24213993