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Synthesis and Antiplasmodial Activity of 1,2,3-Triazole-Naphthoquinone Conjugates

A series of 34 1,2,3-triazole-naphthoquinone conjugates were synthesized via copper-catalyzed cycloaddition (CuAAC). They were evaluated for their in vitro antimalarial activity against chloroquine-sensitive strains of Plasmodium falciparum and against three different tumor cell lines (SKBr-3, MCF-7...

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Detalles Bibliográficos
Autores principales: Oramas-Royo, Sandra, López-Rojas, Priscila, Amesty, Ángel, Gutiérrez, David, Flores, Ninoska, Martín-Rodríguez, Patricia, Fernández-Pérez, Leandro, Estévez-Braun, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864696/
https://www.ncbi.nlm.nih.gov/pubmed/31671684
http://dx.doi.org/10.3390/molecules24213917