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CXCR4 Antagonism to Treat Delayed Fracture Healing

A significant number of fractures develop nonunion. Stem cell homing is regulated through stromal cell-derived factor 1 (SDF1) and its receptor CXCR4. Stem/progenitor cell populations can be endogenously mobilized by administering growth factors with a pharmacological antagonist of CXCR4, AMD3100, w...

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Detalles Bibliográficos
Autores principales: Meeson, Richard, Sanghani-Keri, Anita, Coathup, Melanie, Blunn, Gordon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864747/
https://www.ncbi.nlm.nih.gov/pubmed/30612520
http://dx.doi.org/10.1089/ten.tea.2018.0265