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CXCR4 Antagonism to Treat Delayed Fracture Healing
A significant number of fractures develop nonunion. Stem cell homing is regulated through stromal cell-derived factor 1 (SDF1) and its receptor CXCR4. Stem/progenitor cell populations can be endogenously mobilized by administering growth factors with a pharmacological antagonist of CXCR4, AMD3100, w...
Autores principales: | Meeson, Richard, Sanghani-Keri, Anita, Coathup, Melanie, Blunn, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864747/ https://www.ncbi.nlm.nih.gov/pubmed/30612520 http://dx.doi.org/10.1089/ten.tea.2018.0265 |
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