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Preparation and Evaluation of Carbamazepine Solid Lipid Nanoparticle for Alleviating Seizure Activity in Pentylenetetrazole-Kindled Mice

Objectives: The study aimed to prepare carbamazepine in solid lipid nanoparticle form (CBZ-SLN) in order to enhance its anticonvulsant effect. Method: Eight formulations of CBZ-SLNs were prepared by homogenization and ultra-sonication techniques. Results: The prepared CBZ-SLN showed a high entrapmen...

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Detalles Bibliográficos
Autores principales: Qushawy, Mona, Prabahar, Kousalya, Abd-Alhaseeb, Mohammed, Swidan, Shady, Nasr, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864770/
https://www.ncbi.nlm.nih.gov/pubmed/31684021
http://dx.doi.org/10.3390/molecules24213971