Cargando…

Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides

The synthesis of novel pyrazolylnucleosides 3a–e, 4a–e, 5a–e, and 6a–e are described. The structures of the regioisomers were elucidated by using extensive NMR studies. The pyrazolylnucleosides 5a–e and 6a–e were screened for anticancer activities on sixty human tumor cell lines. The compound 6e sho...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Yogesh, Sharma, Deepti, Kaushik, Kumar, Kumar, Vineet, Jha, Amitabh, Prasad, Ashok K., Len, Christophe, Malhotra, Sanjay V., Wengel, Jesper, Parmar, Virinder S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864788/
https://www.ncbi.nlm.nih.gov/pubmed/31671703
http://dx.doi.org/10.3390/molecules24213922