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Replication Stress and Consequential Instability of the Genome and Epigenome

Cells must faithfully duplicate their DNA in the genome to pass their genetic information to the daughter cells. To maintain genomic stability and integrity, double-strand DNA has to be replicated in a strictly regulated manner, ensuring the accuracy of its copy number, integrity and epigenetic modi...

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Detalles Bibliográficos
Autores principales: Tsegay, Pawlos S., Lai, Yanhao, Liu, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864812/
https://www.ncbi.nlm.nih.gov/pubmed/31717862
http://dx.doi.org/10.3390/molecules24213870