Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)

10-deoxoartemisinin is a semisynthetic derivative of artemisinin that lacks a lactone carbonyl group at the 10-position, and has stronger antimalarial properties than artemisinin. However, 10-deoxoartemisinin has limited utility as a therapeutic agent because of its low solubility and bioavailabilit...

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Detalles Bibliográficos
Autores principales: Bai, Yue, Zhang, Dong, Sun, Peng, Zhao, Yifan, Chang, Xiaoqiang, Ma, Yue, Yang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864820/
https://www.ncbi.nlm.nih.gov/pubmed/31661766
http://dx.doi.org/10.3390/molecules24213874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864820/
https://www.ncbi.nlm.nih.gov/pubmed/31661766
http://dx.doi.org/10.3390/molecules24213874

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