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Synthesis of Enantiomerically Pure N-Boc-Protected 1,2,3-Triaminopropylphosphonates and 1,2-Diamino-3-Hydroxypropylphosphonates

All possible isomers of 1,2,3-tri(N-tert-butoxycarbonylamino)propylphosphonate 6 were synthesized from the respective diethyl [N-(1-phenylethyl)]-1-benzylamino-2,3-epiiminopropylphosphonates 5 via opening the aziridine ring with trimethylsilyl azide (TMSN(3)) followed by hydrogenolysis in the presen...

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Detalles Bibliográficos
Autores principales: Trocha, Aleksandra, Piotrowska, Dorota G., Głowacka, Iwona E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864986/
https://www.ncbi.nlm.nih.gov/pubmed/31731561
http://dx.doi.org/10.3390/molecules24213857