Estimating network changes from lifespan measurements using a parsimonious gene network model of cellular aging

BACKGROUND: Cellular aging is best studied in the budding yeast Saccharomyces cerevisiae. As an example of a pleiotropic trait, yeast lifespan is influenced by hundreds of interconnected genes. However, no quantitative methods are currently available to infer system-level changes in gene networks du...

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Detalles Bibliográficos
Autor principal: Qin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865033/
https://www.ncbi.nlm.nih.gov/pubmed/31747877
http://dx.doi.org/10.1186/s12859-019-3177-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865033/
https://www.ncbi.nlm.nih.gov/pubmed/31747877
http://dx.doi.org/10.1186/s12859-019-3177-7

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