Cargando…
Elamipretide (SS-31) improves mitochondrial dysfunction, synaptic and memory impairment induced by lipopolysaccharide in mice
BACKGROUND: It is widely accepted that mitochondria have a direct impact on neuronal function and survival. Oxidative stress caused by mitochondrial abnormalities play an important role in the pathophysiology of lipopolysaccharide (LPS)-induced memory impairment. Elamipretide (SS-31) is a novel mito...
Autores principales: | Zhao, Weixing, Xu, Zhipeng, Cao, Jiangbei, Fu, Qiang, Wu, Yishuang, Zhang, Xiaoying, Long, Yue, Zhang, Xuan, Yang, Yitian, Li, Yunfeng, Mi, Weidong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865061/ https://www.ncbi.nlm.nih.gov/pubmed/31747905 http://dx.doi.org/10.1186/s12974-019-1627-9 |
Ejemplares similares
-
Elamipretide (SS-31) Improves Functional Connectivity in Hippocampus and Other Related Regions Following Prolonged Neuroinflammation Induced by Lipopolysaccharide in Aged Rats
por: Liu, Yang, et al.
Publicado: (2021) -
The effects of a mitochondrial targeted peptide (elamipretide/SS31) on BAX recruitment and activation during apoptosis
por: Grosser, Joshua A., et al.
Publicado: (2021) -
Elamipretide (SS-31) Ameliorates Isoflurane-Induced Long-Term Impairments of Mitochondrial Morphogenesis and Cognition in Developing Rats
por: Wu, Jing, et al.
Publicado: (2017) -
The mitochondrially targeted peptide elamipretide (SS-31) improves ADP sensitivity in aged mitochondria by increasing uptake through the adenine nucleotide translocator (ANT)
por: Pharaoh, Gavin, et al.
Publicado: (2023) -
Barth syndrome cardiomyopathy: targeting the mitochondria with elamipretide
por: Sabbah, Hani N.
Publicado: (2020)