Cargando…

The role of pyruvate kinase M2 in anticancer therapeutic treatments

Cancer cells are characterized by a high glycolytic rate, which leads to energy regeneration and anabolic metabolism; a consequence of this is the abnormal expression of pyruvate kinase isoenzyme M2 (PKM2). Multiple studies have demonstrated that the expression levels of PKM2 are upregulated in nume...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Qiongli, Luo, Shengping, Tan, Qiuhong, Deng, Jun, Zhou, Sichun, Peng, Mei, Tao, Ting, Yang, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865080/
https://www.ncbi.nlm.nih.gov/pubmed/31788038
http://dx.doi.org/10.3892/ol.2019.10948