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GRIN3B missense mutation as an inherited risk factor for schizophrenia: whole-exome sequencing in a family with a familiar history of psychotic disorders

Glutamate is the most important excitatory neurotransmitter in the brain. The N-methyl-D-aspartate (NMDA) receptor is a glutamate-gated ionotropic cation channel that is composed of several subunits and modulated by a glycine binding site. Many forms of synaptic plasticity depend on the influx of ca...

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Detalles Bibliográficos
Autores principales: HORNIG, TOBIAS, GRÜNING, BJÖRN, KUNDU, KOUSIK, HOUWAART, TORSTEN, BACKOFEN, ROLF, BIBER, KNUT, NORMANN, CLAUS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865172/
https://www.ncbi.nlm.nih.gov/pubmed/28132660
http://dx.doi.org/10.1017/S0016672316000148