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Role of L-Type Amino Acid Transporter 1 (LAT1) for the Selective Cytotoxicity of Sesamol in Human Melanoma Cells

Sesamol is effective against melanoma cells with less damage to normal cells. The underlying selective cytotoxicity of sesamol in melanoma vs. non-cancerous cells is undefined. Melanoma cells differ from normal cells by over-expression of the L-type amino acid transporter 1 (LAT1). We sought to clar...

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Detalles Bibliográficos
Autores principales: Srisongkram, Tarapong, Weerapreeyakul, Natthida, Kärkkäinen, Jussi, Rautio, Jarkko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865181/
https://www.ncbi.nlm.nih.gov/pubmed/31717859
http://dx.doi.org/10.3390/molecules24213869