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Nucleophilic Arylation of Halopurines Facilitated by Brønsted Acid in Fluoroalcohol
Various aryl-substituted purine derivatives were synthesized through the direct arylation of halopurines with aromatic compounds, facilitated by the combination of triflic acid and fluoroalcohol. This metal-free method is complementary to conventional coupling reactions using metal catalysts and rea...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865213/ https://www.ncbi.nlm.nih.gov/pubmed/31652675 http://dx.doi.org/10.3390/molecules24213812 |