MicroRNA-27a-3p Downregulation Inhibits Inflammatory Response and Hippocampal Neuronal Cell Apoptosis by Upregulating Mitogen-Activated Protein Kinase 4 (MAP2K4) Expression in Epilepsy: In Vivo and In Vitro Studies

BACKGROUND: This study aimed to discover the effect and mechanism of microRNA-27a-3p (miR-27a-3p) in epilepsy. MATERIAL/METHODS: To perform our investigation, in vivo and in vitro models of epilepsy were induced using kainic acid (KA). Expression of miR-27a-3p in the hippocampus of epileptic rats or...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Zhou, Nina, Yang, Ping, Deng, Lanqiuzi, Liu, Ganzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865231/
https://www.ncbi.nlm.nih.gov/pubmed/31710596
http://dx.doi.org/10.12659/MSM.916458

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865231/
https://www.ncbi.nlm.nih.gov/pubmed/31710596
http://dx.doi.org/10.12659/MSM.916458

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