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Inhibition of microRNA-221-5p induces osteogenic differentiation by directly targeting smad3 in myeloma bone disease mesenchymal stem cells

Myeloma bone disease (MBD) is one of the clinical features of multiple myeloma, which contributes to the attenuation of osteoblast function. Bone marrow mesenchymal stem cells exhibit a high potential for differentiation into osteoblasts. A number of studies have reported that microRNAs (miRs) serve...

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Detalles Bibliográficos
Autores principales: Fan, Fang-Yi, Deng, Rui, Lai, Si-Han, Wen, Qin, Zeng, Yunjing, Gao, Lei, Liu, Yao, Kong, Peiyan, Zhong, Jiangfan, Su, Yi, Zhang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865756/
https://www.ncbi.nlm.nih.gov/pubmed/31788114
http://dx.doi.org/10.3892/ol.2019.10992