Oleanolic Acid Acetate Exerts Anti-Inflammatory Activity via IKKα/β Suppression in TLR3-Mediated NF-κB Activation

Oleanolic acid acetate (OAA), a major triterpenoid compound of Vigna angularis (azuki bean, V. angularis), has been shown to downregulate inflammatory responses in macrophages. Here, we show the molecular basis for the effect of OAA on Toll-like receptor (TLR) downstream signaling. OAA treatment sig...

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Detalles Bibliográficos
Autores principales: Lim, Hyung Jin, Jang, Hyun-Jae, Kim, Mi Hwa, Lee, Soyoung, Lee, Seung Woong, Lee, Seung-Jae, Rho, Mun-Chual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866124/
https://www.ncbi.nlm.nih.gov/pubmed/31694243
http://dx.doi.org/10.3390/molecules24214002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6866124/
https://www.ncbi.nlm.nih.gov/pubmed/31694243
http://dx.doi.org/10.3390/molecules24214002

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