Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint

The restricted access of regulatory factors to their binding sites on DNA wrapped around the nucleosomes is generally interpreted in terms of molecular shielding exerted by nucleosomal structure and internucleosomal interactions. Binding of proteins to DNA often includes intercalation of hydrophobic...

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Detalles Bibliográficos
Autores principales: Bosire, Rosevalentine, Nánási, Péter, Imre, László, Dienes, Beatrix, Szöőr, Árpád, Mázló, Anett, Kovács, Attila, Seidel, Ralf, Vámosi, György, Szabó, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867626/
https://www.ncbi.nlm.nih.gov/pubmed/31747397
http://dx.doi.org/10.1371/journal.pone.0224936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867626/
https://www.ncbi.nlm.nih.gov/pubmed/31747397
http://dx.doi.org/10.1371/journal.pone.0224936

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