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Threat Memory Reminder Under Matrix Metalloproteinase 9 Inhibitor Doxycycline Globally Reduces Subsequent Memory Plasticity

Associative memory can be rendered malleable by a reminder. Blocking the ensuing reconsolidation process is suggested as a therapeutic target for unwanted aversive memories. Matrix metalloproteinase-9 (MMP-9) is required for structural synapse remodeling involved in memory consolidation. Inhibiting...

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Detalles Bibliográficos
Autores principales: Bach, Dominik R., Näf, Monika, Deutschmann, Markus, Tyagarajan, Shiva K., Quednow, Boris B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867817/
https://www.ncbi.nlm.nih.gov/pubmed/31615840
http://dx.doi.org/10.1523/JNEUROSCI.1285-19.2019