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Threat Memory Reminder Under Matrix Metalloproteinase 9 Inhibitor Doxycycline Globally Reduces Subsequent Memory Plasticity
Associative memory can be rendered malleable by a reminder. Blocking the ensuing reconsolidation process is suggested as a therapeutic target for unwanted aversive memories. Matrix metalloproteinase-9 (MMP-9) is required for structural synapse remodeling involved in memory consolidation. Inhibiting...
Autores principales: | Bach, Dominik R., Näf, Monika, Deutschmann, Markus, Tyagarajan, Shiva K., Quednow, Boris B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867817/ https://www.ncbi.nlm.nih.gov/pubmed/31615840 http://dx.doi.org/10.1523/JNEUROSCI.1285-19.2019 |
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