A microtranslatome coordinately regulates sodium and potassium currents in the human heart

Catastrophic arrhythmias and sudden cardiac death can occur with even a small imbalance between inward sodium currents and outward potassium currents, but mechanisms establishing this critical balance are not understood. Here, we show that mRNA transcripts encoding I(Na) and I(Kr) channels (SCN5A an...

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Detalles Bibliográficos
Autores principales: Eichel, Catherine A, Ríos-Pérez, Erick B, Liu, Fang, Jameson, Margaret B, Jones, David K, Knickelbine, Jennifer J, Robertson, Gail A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867827/
https://www.ncbi.nlm.nih.gov/pubmed/31670657
http://dx.doi.org/10.7554/eLife.52654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867827/
https://www.ncbi.nlm.nih.gov/pubmed/31670657
http://dx.doi.org/10.7554/eLife.52654

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