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Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction

Dendritic cells (DCs) and macrophages as well as osteoclasts (OCs) are emerging as target cells of HIV-1 involved in virus transmission, dissemination, and establishment of persistent tissue virus reservoirs. While these myeloid cells are poorly infected by cell-free viruses because of the high expr...

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Detalles Bibliográficos
Autores principales: Xie, Maorong, Leroy, Héloïse, Mascarau, Rémi, Woottum, Marie, Dupont, Maeva, Ciccone, Camille, Schmitt, Alain, Raynaud-Messina, Brigitte, Vérollet, Christel, Bouchet, Jérôme, Bracq, Lucie, Benichou, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867896/
https://www.ncbi.nlm.nih.gov/pubmed/31744918
http://dx.doi.org/10.1128/mBio.02457-19