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Towards precision medicine: interrogating the human genome to identify drug pathways associated with potentially functional, population-differentiated polymorphisms

Drug response variations amongst different individuals/populations are influenced by several factors including allele frequency differences of single nucleotide polymorphisms (SNPs) that functionally affect drug-response genes. Here, we aim to identify drugs that potentially exhibit population diffe...

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Detalles Bibliográficos
Autores principales: Bachtiar, Maulana, Ooi, Brandon Nick Sern, Wang, Jingbo, Jin, Yu, Tan, Tin Wee, Chong, Samuel S., Lee, Caroline G. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867962/
https://www.ncbi.nlm.nih.gov/pubmed/31578463
http://dx.doi.org/10.1038/s41397-019-0096-y