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Modeling Brain Somatic Mosaicism With Cerebral Organoids, Including a Note on Mutant Microglia
The brain is a genomic mosaic. Cell-to-cell genomic differences, which are the result of somatic mutations during development and aging, contribute to cellular diversity in the nervous system. This genomic diversity has important implications for nervous system development, function, and disease. Br...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868038/ https://www.ncbi.nlm.nih.gov/pubmed/31798412 http://dx.doi.org/10.3389/fnmol.2019.00277 |