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Livin Regulates H2A.X(Y142) Phosphorylation and Promotes Autophagy in Colon Cancer Cells via a Novel Kinase Activity

Objective: To investigate Livin-mediated regulation of H2A.X(Y142) phosphorylation via a novel kinase activity and its effect on autophagy in colon cancer cells. Methods: The interaction between Livin and H2A.X was tested by immunoprecipitation. H2A.X–/– HCT116 cells were transfected with human infl...

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Detalles Bibliográficos
Autores principales: Ge, Yang, Liu, Bao-lin, Cui, Jun-peng, Li, Shu-qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868062/
https://www.ncbi.nlm.nih.gov/pubmed/31799193
http://dx.doi.org/10.3389/fonc.2019.01233