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Livin Regulates H2A.X(Y142) Phosphorylation and Promotes Autophagy in Colon Cancer Cells via a Novel Kinase Activity
Objective: To investigate Livin-mediated regulation of H2A.X(Y142) phosphorylation via a novel kinase activity and its effect on autophagy in colon cancer cells. Methods: The interaction between Livin and H2A.X was tested by immunoprecipitation. H2A.X–/– HCT116 cells were transfected with human infl...
Autores principales: | Ge, Yang, Liu, Bao-lin, Cui, Jun-peng, Li, Shu-qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868062/ https://www.ncbi.nlm.nih.gov/pubmed/31799193 http://dx.doi.org/10.3389/fonc.2019.01233 |
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