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Negative frequency dependent selection on plasmid carriage and low fitness costs maintain extended spectrum β-lactamases in Escherichia coli

Plasmids may maintain antibiotic resistance genes in bacterial populations through conjugation, in the absence of direct selection pressure. However, the costs and benefits of conjugation for plasmid and bacterial fitness are not well understood. Using invasion and competition experiments with plasm...

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Detalles Bibliográficos
Autores principales: Dimitriu, Tatiana, Medaney, Frances, Amanatidou, Elli, Forsyth, Jessica, Ellis, Richard J., Raymond, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868128/
https://www.ncbi.nlm.nih.gov/pubmed/31748602
http://dx.doi.org/10.1038/s41598-019-53575-7