Airway epithelial regeneration requires autophagy and glucose metabolism

Efficient repair of injured epithelium by airway progenitor cells could prevent acute inflammation from progressing into chronic phase in lung. Here, we used small molecules, genetic loss-of-function, organoid cultures, and in vivo lung-injury models to show that autophagy is essential for maintaini...

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Detalles Bibliográficos
Autores principales: Li, Kuan, Li, Minmin, Li, Wenli, Yu, Hongzhi, Sun, Xin, Zhang, Qiuyang, Li, Yu, Li, Xue, Li, Yue, Abel, E. Dale, Wu, Qi, Chen, Huaiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868131/
https://www.ncbi.nlm.nih.gov/pubmed/31748541
http://dx.doi.org/10.1038/s41419-019-2111-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868131/
https://www.ncbi.nlm.nih.gov/pubmed/31748541
http://dx.doi.org/10.1038/s41419-019-2111-2

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