Pharmacokinetics of Exenatide in nonhuman primates following its administration in the form of sustained-release PT320 and Bydureon

The time-dependent (30 min - day 84) plasma profile of PT320, a sustained-release (SR)-Exenatide formulation under clinical development for treatment of neurodegenerative disorders, was evaluated in nonhuman primates after a single subcutaneous dose and was compared to Bydureon. Exenatide release fr...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yazhou, Vaughan, Kelli L., Tweedie, David, Jung, Jin, Kim, Hee Kyung, Choi, Ho-Il, Kim, Dong Seok, Mattison, Julie A., Greig, Nigel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868133/
https://www.ncbi.nlm.nih.gov/pubmed/31748513
http://dx.doi.org/10.1038/s41598-019-53356-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868133/
https://www.ncbi.nlm.nih.gov/pubmed/31748513
http://dx.doi.org/10.1038/s41598-019-53356-2

Ejemplares similares