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Pharmacokinetics of Exenatide in nonhuman primates following its administration in the form of sustained-release PT320 and Bydureon
The time-dependent (30 min - day 84) plasma profile of PT320, a sustained-release (SR)-Exenatide formulation under clinical development for treatment of neurodegenerative disorders, was evaluated in nonhuman primates after a single subcutaneous dose and was compared to Bydureon. Exenatide release fr...
Autores principales: | Li, Yazhou, Vaughan, Kelli L., Tweedie, David, Jung, Jin, Kim, Hee Kyung, Choi, Ho-Il, Kim, Dong Seok, Mattison, Julie A., Greig, Nigel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868133/ https://www.ncbi.nlm.nih.gov/pubmed/31748513 http://dx.doi.org/10.1038/s41598-019-53356-2 |
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