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Characterization of the expression of LAT1 as a prognostic indicator and a therapeutic target in renal cell carcinoma

Large neutral amino acid transporter 1 (LAT1, SLC7A5) is abundantly expressed in various types of cancer, and it has been thought to assist cancer progression through its activity for uptake of neutral amino acids. However, the roles of LAT1 in renal cell carcinoma (RCC) prognosis and treatment rema...

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Detalles Bibliográficos
Autores principales: Higuchi, Kosuke, Sakamoto, Shinichi, Ando, Keisuke, Maimaiti, Maihulan, Takeshita, Nobushige, Okunushi, Kentaro, Reien, Yoshie, Imamura, Yusuke, Sazuka, Tomokazu, Nakamura, Kazuyoshi, Matsushima, Jun, Furihata, Tomomi, Ikehara, Yuzuru, Ichikawa, Tomohiko, Anzai, Naohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868143/
https://www.ncbi.nlm.nih.gov/pubmed/31748583
http://dx.doi.org/10.1038/s41598-019-53397-7