Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice

Mounting evidence suggests that antiretroviral therapy (ART) drugs may contribute to the prevalence of HIV-associated neurological dysfunction. The HIV envelope glycoprotein (gp120) is neurotoxic and has been linked to alterations in mitochondrial function and increased inflammatory gene expression,...

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Detalles Bibliográficos
Autores principales: Fields, Jerel Adam, Swinton, Mary K., Carson, Aliyah, Soontornniyomkij, Benchawanna, Lindsay, Charmaine, Han, May Madi, Frizzi, Katie, Sambhwani, Shrey, Murphy, Anne, Achim, Cristian L., Ellis, Ronald J., Calcutt, Nigel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868155/
https://www.ncbi.nlm.nih.gov/pubmed/31748578
http://dx.doi.org/10.1038/s41598-019-53466-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868155/
https://www.ncbi.nlm.nih.gov/pubmed/31748578
http://dx.doi.org/10.1038/s41598-019-53466-x

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