ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation

Zar1 was one of the earliest mammalian maternal-effect genes to be identified. Embryos derived from Zar1-null female mice are blocked before zygotic genome activation; however, the underlying mechanism remains unclear. By knocking out Zar1 and its homolog Zar2 in mice, we revealed a novel function o...

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Detalles Bibliográficos
Autores principales: Rong, Yan, Ji, Shu-Yan, Zhu, Ye-Zhang, Wu, Yun-Wen, Shen, Li, Fan, Heng-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868374/
https://www.ncbi.nlm.nih.gov/pubmed/31598710
http://dx.doi.org/10.1093/nar/gkz863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868374/
https://www.ncbi.nlm.nih.gov/pubmed/31598710
http://dx.doi.org/10.1093/nar/gkz863

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