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Direct interplay between stereochemistry and conformational preferences in aminoacylated oligoribonucleotides
To address the structural and dynamical consequences of amino-acid attachment at 2′- or 3′-hydroxyls of the terminal ribose in oligoribonucleotides, we have performed an extensive set of molecular dynamics simulations of model aminoacylated RNA trinucleotides. Our simulations suggest that 3′-modifie...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868383/ https://www.ncbi.nlm.nih.gov/pubmed/31612955 http://dx.doi.org/10.1093/nar/gkz902 |