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Branch site bulge conformations in domain 6 determine functional sugar puckers in group II intron splicing
Although group II intron ribozymes are intensively studied the question how structural dynamics affects splicing catalysis has remained elusive. We report for the first time that the group II intron domain 6 exists in a secondary structure equilibrium between a single- and a two-nucleotide bulge con...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868427/ https://www.ncbi.nlm.nih.gov/pubmed/31665419 http://dx.doi.org/10.1093/nar/gkz965 |