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Control of ϕC31 integrase-mediated site-specific recombination by protein trans-splicing

Serine integrases are emerging as core tools in synthetic biology and have applications in biotechnology and genome engineering. We have designed a split-intein serine integrase-based system with potential for regulation of site-specific recombination events at the protein level in vivo. The ϕC31 in...

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Detalles Bibliográficos
Autores principales: Olorunniji, Femi J, Lawson-Williams, Makeba, McPherson, Arlene L, Paget, Jane E, Stark, W Marshall, Rosser, Susan J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868429/
https://www.ncbi.nlm.nih.gov/pubmed/31667500
http://dx.doi.org/10.1093/nar/gkz936