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New insights into protein–DNA binding specificity from hydrogen bond based comparative study

Knowledge of protein–DNA binding specificity has important implications in understanding DNA metabolism, transcriptional regulation and developing therapeutic drugs. Previous studies demonstrated hydrogen bonds between amino acid side chains and DNA bases play major roles in specific protein–DNA int...

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Detalles Bibliográficos
Autores principales: Lin, Maoxuan, Guo, Jun-tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868434/
https://www.ncbi.nlm.nih.gov/pubmed/31665426
http://dx.doi.org/10.1093/nar/gkz963