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New insights into protein–DNA binding specificity from hydrogen bond based comparative study
Knowledge of protein–DNA binding specificity has important implications in understanding DNA metabolism, transcriptional regulation and developing therapeutic drugs. Previous studies demonstrated hydrogen bonds between amino acid side chains and DNA bases play major roles in specific protein–DNA int...
Autores principales: | Lin, Maoxuan, Guo, Jun-tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868434/ https://www.ncbi.nlm.nih.gov/pubmed/31665426 http://dx.doi.org/10.1093/nar/gkz963 |
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