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Streamlining effects of extra telomeric repeat on telomeric DNA folding revealed by fluorescence-force spectroscopy

A human telomere ends in a single-stranded 3′ tail, composed of repeats of T(2)AG(3). G-quadruplexes (GQs) formed from four consecutive repeats have been shown to possess high-structural and mechanical diversity. In principle, a GQ can form from any four repeats that are not necessarily consecutive....

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Detalles Bibliográficos
Autores principales: Mitra, Jaba, Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868435/
https://www.ncbi.nlm.nih.gov/pubmed/31617570
http://dx.doi.org/10.1093/nar/gkz906