RB, p130 and p107 differentially repress G1/S and G2/M genes after p53 activation

Cell cycle gene expression occurs in two waves. The G1/S genes encode factors required for DNA synthesis and the G2/M genes contribute to mitosis. The Retinoblastoma protein (RB) and DREAM complex (DP, RB-like, E2F4 and MuvB) cooperate to repress all cell cycle genes during G1 and inhibit entry into...

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Detalles Bibliográficos
Autores principales: Schade, Amy E, Fischer, Martin, DeCaprio, James A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868438/
https://www.ncbi.nlm.nih.gov/pubmed/31667499
http://dx.doi.org/10.1093/nar/gkz961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868438/
https://www.ncbi.nlm.nih.gov/pubmed/31667499
http://dx.doi.org/10.1093/nar/gkz961

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