Low temperature isothermal amplification of microsatellites drastically reduces stutter artifact formation and improves microsatellite instability detection in cancer

Microsatellites are polymorphic short tandem repeats of 1–6 nucleotides ubiquitously present in the genome that are extensively used in living organisms as genetic markers and in oncology to detect microsatellite instability (MSI). While the standard analysis method of microsatellites is based on PC...

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Detalles Bibliográficos
Autores principales: Daunay, Antoine, Duval, Alex, Baudrin, Laura G, Buhard, Olivier, Renault, Victor, Deleuze, Jean-François, How-Kit, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868440/
https://www.ncbi.nlm.nih.gov/pubmed/31584085
http://dx.doi.org/10.1093/nar/gkz811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868440/
https://www.ncbi.nlm.nih.gov/pubmed/31584085
http://dx.doi.org/10.1093/nar/gkz811

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