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A novel and translational role for autophagy in antisense oligonucleotide trafficking and activity

Endocytosis is a mechanism by which cells sense their environment and internalize various nutrients, growth factors and signaling molecules. This process initiates at the plasma membrane, converges with autophagy, and terminates at the lysosome. It is well-established that cellular uptake of antisen...

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Detalles Bibliográficos
Autores principales: Ochaba, Joseph, Powers, Andrew F, Tremble, Kaitlyn A, Greenlee, Sarah, Post, Noah M, Matson, John E, MacLeod, A Robert, Guo, Shuling, Aghajan, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868497/
https://www.ncbi.nlm.nih.gov/pubmed/31612951
http://dx.doi.org/10.1093/nar/gkz901